The Center for the Biology of Nematode Parasitism exploits opportunities in post-genomic biology.

This Center integrates knowledge and research of free-living and parasitic nematodes and exploits model systems to make strides in understanding the basic mechanism of parasitism.

The Center's Research

The Center's research interests include:

• nematode biology and development;
• genome organization and evolution;
• structure-function relationships;
• host-parasite interactions;
• evolution of parasitism;
• host responses and resistance/susceptibility to pathogens; and,
• plant development.

Comprehensive Transcriptome Profiling in Tomato Reveals a Role for Glycosyltransferase in Mi-Mediated Nematode Resistance Plant Physiology 144:1079-1092 (2007)
Jennifer E. Schaff, Dahlia M. Nielsen, Chris P. Smith, Elizabeth H. Scholl and David McK. Bird

Phylogenetic Analysis of Pasteuria penetrans by Use of Multiple Genetic Loci Journal of Bacteriology, August 2005, p. 5700-5708, Vol. 187, No. 16
Lauren Charles, Ignazio Carbone, Keith G. Davies, David Bird, Mark Burke, Brian R. Kerry, and Charles H. Opperman1

Root-knot nematodes and bacterial Nod factors elicit common signal transduction events in Lotus japonicus PNAS | February 22, 2005 | vol. 102 | no. 8 | 3147-3152
Ravisha R. Weerasinghe, David McK. Bird and Nina S. Allen

Virulence Genes in Heterodera glycines: Allele Frequencies and Ror Gene Groups Among Field Isolates and Inbred Lines (pdf file)
Phytopathology | February 2005 | Volume 95, Number 2
K. Dong, K. R. Barker, and C. H. Opperman. Pages 186-191.

Lotus japonicus: A New Model to Study Root-Parasitic Nematodes
Dasharath Prasad Lohar and David McK. Bird
Plant and Cell Physiology, 2003, Vol. 44, No. 11 1176-1184

Horizontally transferred genes in plant-parasitic nematodes: a high-throughput genomic approach
Elizabeth H Scholl, Jeffrey L Thorne, James P McCarter, and David Mck Bird
Genome Biology 2003, Vol. 4, Issue 6

Cytokinins play opposite roles in lateral root formation, and nematode and Rhizobial symbioses
Lohar, Dasharath Prasad, Schaff, Jennifer E., Laskey, James G., Kieber, Joseph J., Bilyeu, Kristin D., Bird, David McK.
The Plant Journal 38 (2), 203-214. (2004)

Model systems in agriculture: Lessons from worms.
Bird, David McK.
Annals of Applied Biology 146 (2), 147-154. (2005)

Resolving tylenchid evolutionary relationships through multiple gene analysis derived from EST data
Elizabeth H. Scholl and David McK. Bird
In Press, Corrected Proof, Available online 3 May 2005

Plant Parasitic Nematodes: Habitats, Hormones, and Horizontally-Acquired Genes
David McKenzie Bird, Hinanit Koltai
Journal of Plant Growth Regulation, Volume 19, Issue 2, Jun 2000, Pages 183 - 194

Alkahest NuclearBLAST : a user-friendly BLAST management and analysis system
Diener SE, Houfek TD, Kalat SE, Windham DE, Burke M, Opperman C, Dean RA
BMC Bioinformatics 2005, 6:147 (15 June 2005)

The Center for the Biology of Nematode Parasitism is located on NCSU's Centennial Campus

• technological innovation and transfer;
• real-world teaching and learning;
• sound business investment; and,
• greater quality of life for North Carolina and beyond.
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  The unique master plan for this environmentally sensitive, mixed-use, academic village responds to the professional, educational and recreational needs of the University's faculty, staff and student body, as well as those of corporate and government affiliates whose presence on Centennial Campus adds to its vigor and effectiveness.
  
  Centennial Campus is providing a new dimension of excellence for the 21st century in the performance of North Carolina State University's land-grant mission of teaching, research and service to the people of North Carolina.